Anagen effluvium secondary to Gloriosa superba ingestion.

Colchicine cardiotoxicity following ingestion of Gloriosa superba tubers.

The clinical features of colchicine toxicity in a patient following ingestion of Gloriosa superba tubers are described. Gastroenteritis, acute renal failure, cardiotoxicity and haematological abnormalities were the main toxic manifestations. There was no hypotension and no neurological manifestations. Electrocardiographic changes were noteworthy and have not been reported previously.

Quantification of Colchicine in Seed and Tuber samples of Gloriosa superba by High Performance Liquid Chromatography method

To quantify the colchicine (alkaloid) present in Gloriosa superba by High Performance Liquid Chromatography (HPLC) method. Gloriosa superba species are known for their content of colchicine, a valuable alkaloid in the seeds and tubers (corms). HPLC analysis was carried out to confirm the presence of colchicine in Gloriosa superba. Treatment of gibberellic acid and Psedomonas aerugenosa improved...

Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning.

Improved growth and colchicine concentration in Gloriosa superba on mycorrhizal inoculation supplemented with phosphorus-fertilizer.

BACKGROUND Gloriosa superba produces an array of alkaloids including colchicine, a compound of interest in the treatment of various diseases. The tuber of Gloriosa superba is a rich source of colchicine which has shown anti-gout, anti-inflammatory, and anti-tumor activity. However, this promising compound remains expensive and Gloriosa superba is such a good source in global scale. Increase in ...

Azathioprine induced anagen effluvium and its association with myelosuppression

Dear Editor, Azathioprine, a steroid sparing immunosuppressant, is used in organ transplantation and various immunological diseases like pemphigus vulgaris, pemphigus foliaceous, vitiligo, lichen planus, and alopecia areata. Anagen effluvium (AE) is the abrupt loss of hairs in their growing phase most commonly due to chemotherapy and radiation 1. Azathioprine can cause AE in association with my...